Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI)
National Institutes of Health
The global aim of Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) is to test and refine Common Data Elements (CDEs), neuroimaging standards, and best practices for genetics and proteomics in Traumatic Brain Injury (TBI) studies. The investigators will create and expand existing repositories for patient data to provide necessary materials for the improvement of clinical research for the entire spectrum of TBI. Ultimately, data collected in TRACK-TBI will aid in the determination of which tests, treatments, services, and classifications are effective and appropriate for which TBI.
Testing and validating of TBI-CDEs will be performed in a multi-center prospective observational study with 3 TBI Centers (San Francisco General Hospital (SFGH), University of Pittsburgh Medical Center (UPMC), University Medical Center Brackenridge (UMCB)) and a TBI Rehabilitation Center (Mount Sinai Rehabilitation Center (MSMC)). The study will collect data from 3000 subjects and controls of all ages. This project has the potential to revolutionize and substantially advance clinical research in TBI across the broad spectrum of injury and disciplines. TRACK-TBI will facilitate and advance both research and health care delivery in the ever-developing field to more correctly serve today’s TBI population. Already, TRACK-TBI researchers have made progress toward more useful classification and prognosis of TBI.
“This is the first truly global initiative dedicated to accelerating the pace of discovery around TBI. TRACK TBI-II will harness the wealth of knowledge we now have access to through imaging, laboratory and behavioral technologies to gain a better understanding of the relationship between specific injury profiles and treatment interventions most likely to be effective. I have every expectation that this international effort will favorably impact one of the most devastating public health problems of our time,” said Dr. Joseph Giacino of Spaulding Rehabilitation Hospital.